The isolation and structure elucidation of macrocyclic lactone antibiotic, A26771B.

نویسندگان

  • K H Michel
  • P V Demarco
  • R Nagarjan
چکیده

The isolation, biological properties and structure elucidation of a sixteen-membered macrocyclic lactone antibiotic, designated A26771B (1), obtained from Penicillium turbatum are discussed.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Isolation and identification macrocyclic spermine alkaloid(protoverbine) from verbascum speciosum.

The 17-membered macrocyclic spermine alkaloid protoverbine (8-phenyl-1,5,9,13-tetra azacycloheptadecan-6-one) was isolated From the aerial part of verbascum speciosum. The natural polyamines are ubiquitous bases reported to have several important functions in animals, plants and microorganisms. They are involved in processes of transcription and translation in protein synthesis and influence gr...

متن کامل

PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. II. Isolation, physico-chemical properties and structure elucidation.

A new macrolide antibiotic, PC-766B, was isolated from the cells of Nocardia brasiliensis SC-4710 by acetone extraction, and purified by gel filtration, silica gel chromatography, HPLC and TLC. The structure of PC-766B was determined by NMR spectral analysis to be a new class of the hygrolidin family antibiotics. PC-766B had a 16-membered macrocyclic lactone ring, a 6-membered hemiketal ring an...

متن کامل

Isolation, physico-chemical properties and structure elucidation studies on HA-2-91 , a new tetraene polyene antifungal antibiotic produced by Streptomyces arenae var ukrainiana

Polyene antibiotics a re characterized to have 26 to 38 membered macrocyclic lactone ring contain ing 3 to 8 conjugated double bonds t and most of them possess remarkable antifungal activity. The polyenes are grouped according to the number of double bonds present in the molecule and it has been rep.orted that the an tifungal activity increases s ignificantl y with the presence of more conjugat...

متن کامل

Isolation and structure elucidation of a new alkaloid from the Indonesian Blue-Green Alga Arthrospira platensis

A new alkaloid (1) and two known compounds (2 and 3) were isolated from the blue-greenalga Arthrospira platensis. Their structures were determined on the basis of spectroscopic data.According to the obtained data and values in the literature, the compounds were concluded to beeckol.

متن کامل

Isolation and Structure Elucidation of Secondary Metabolites from Echinophora platyloba DC from Iran

Background: Echinophora platyloba DC (Apiaceae) is one of the two endemic species of Echinophora genus in Iran. It has many folkloric uses and several biological activities but there is no information about its phytoconstituents. Objective: In this work some of the secondary metabolites were isolated, purified and identified from n-hexane, ethyl acetate and methanol extracts from the aerial pa...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • The Journal of antibiotics

دوره 30 7  شماره 

صفحات  -

تاریخ انتشار 1977